Severe acute respiratory syndrome (SARS)

Severe acute respiratory syndrome (SARS) : – severe acute respiratory syndrome (SARS) is a communicable virus disease caused by a new strain of coronavirus which different considerably e in genetic structure from previously recognise coronavirus. The most common symptoms and patient progressing SARS includes.

Severe acute respiratory syndrome (SARS)
Severe acute respiratory syndrome (SARS)
  • Fever
  • Malaise
  • Chills
  • Headache
  • Myalgia
  • Dizziness
  • Cough
  • Sore throat
  • Running nose
Severe acute respiratory syndrome (SARS)
Severe acute respiratory syndrome (SARS)

In some cases acute respiratory distress requiring ventilator support. It is capable of causing death in as many as 10% cases.

Chest x ray findings typically begin with a small unilateral patchy shadowing and progress over 1-2 days to become bilateral and generalized with interstitial conflucent infiltration adult respiratory destress syndrome has been observed in a number of patients in the end stage.

Transmission

The SARS- CoV appears to be transmitted primarily by large droplet is spread, although surface contamination and possibly airbros spread may play a role.

Prognosis

The overall Mortality rate of identified case is about 14% mortality is age related, ranging from less than 1% in person under 24 years of age to Greater than 50% in persons over 65 years of age.

Treatment

There is no specific treatment currently available for SARS management consist of supportive care and appropriate infection control measure to prevent spread.

In all series of SARS cases describes to date, therapy has involved bread spectrum antibiotics include a fluoroquinoline or macrolide. The antiviral drug Ribavirin has been used in most patient treated in Hongkong and in Toronto without evidence of efficacy.

Subsequent studies with Ribavirin show no activity against the virus in vitro and a retrospective analysis of the epidemic in Toronto suggests worse outcome in patient who receive the drug.

Prevention

  1. Prompt identification of person with sars their movement and contacts.
  2. Effective isolation of SARS patients in hospitals
  3. Appropriate protections of medical staff treating these patients.
  4. Comprehensive Identification and isolation of suspected SARS cases.
  5. Simple hygienic measure such as hand washing after touching patient use of appropriate and well fitted mask and introduction of infection control measures.
  6. Exit Screening of international travellers.
  7. Timely and decorator reporting and sharing of information with other authorities and / or governments.