GPAT Exam 2021 Mock Test, Sample Paper 1

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By giving which you can increase your knowledge for GPAT EXAM, prepare yourself well, this test can prove to be very good for you, Most of the questions given in this test are taken from the old question paper of GPAT EXAM, so that you will also know what type of questions are asked in GPAT EXAM .

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Created on By Ranu Gupta

GPAT Exam 1

Based On previous GPAT exam

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Type II glass containers are

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Dimethyl sulfoxide acts as penetration enhancer for topical formulations by

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As per European Pharmacopoeia technical guide, substance stored at 25°C for 24 hours at 80% RH, called very hygroscopic when increase in weight is

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Lakes of Dyes available commercially contain maximum upto…………of pure dye.

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Following statement is more accurate with respect to limitations of Arrhenius relationship for stability prediction

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Following statement is more accurate with respect to limitations of Arrhenius relationship for stability prediction

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Relative sweetness of sucrose, to saccharin :

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Violin gut is obtained from intestine of

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SCHICK Test Toxin is a sterile Filtrate from a culture of

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An excipient Ludipress used for liquid Dosage form is a coprocessed excipient of

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Pyrogens present in containers can be destroyed by heating the containers at

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Following is the important sterol in faeces formed from cholesterol by bacteria in lower intestine:

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The unequal attractive forces acting on the molecules at the surface of liquid gas interface when compared with molecular forces in the bulk of the liquid is due to:

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Following is the important sterol in faeces formed from cholesterol by bacteria in lower intestine:

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The 'Crenulation' effect on the cell wall is caused by_______________ solutions and this effect is__________________.

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In capsule making the Bloom strength of gelatin is proportional to molecular weight of the gelatin and is a measure of the;

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Choose the wrong statement from the following with regard to Amorphous solids

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Which of the following is not a fundamental (primary) factor considered for selection of a location for the construction of pharmaceutical or chemical plant

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The temperature dependence and the theory of viscosity is expressed by the following

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Production of Acetyl methyl carbinol can be detected by which of the following test

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The drug concentration between Minimum effective concentration (MEC) and maximum safe concentration (MSC) is called

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The following gram positive bacteria species is positive for the coagulase test (a test for the ability of bacteria to cause blood plasma to clot)

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The version of GMP in India that describe requirement of factory premises for manufacture of cosmetics

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This fungus is also known as opportunistic pathogen, often isolated from warm-blooded animals.

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Which of the following will result in very closest value to the Glomerular Filteration Rate (GFR) ?

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While studying solid state physicochemical properties, the packing property of drug include

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The Acidic polymers of Ribitol/Glycerol phosphate present in Gram positive microorganism are known as

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The Acidic polymers of Ribitol/Glycerol phosphate present in Gram positive microorganism are known as

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Pharmacokinetics is:

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What does “pharmacokinetics” include?

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What does “pharmacokinetics” include?

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What does “pharmacokinetics” include?

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What does “pharmacokinetics” include?

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The main mechanism of most drugs absorption in GI tract is:

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What kind of substances can’t permeate membranes by passive diffusion?

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A hydrophilic medicinal agent has the following property:

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What is implied by «active transport»?

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What does the term “bioavailability” mean?

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The reasons determing bioavailability are:

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Pick out the appropriate alimentary route of administration when passage of drugs through liver is minimized:

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Which route of drug administration is most likely to lead to the first-pass effect?

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What is characteristic of the oral route?

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Tick the feature of the sublingual route:

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Pick out the parenteral route of medicinal agent administration:

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Parenteral administration:

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What is characteristic of the intramuscular route of drug administration?

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. Intravenous injections are more suitable for oily solutions:

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Correct statements listing characteristics of a particular route of drug administration include all of the following EXCEPT:

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Most of drugs are distributed homogeneously.

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Biological barriers include all except:

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What is the reason of complicated penetration of some drugs through brain-blood barrier?

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The volume of distribution (Vd) relates:

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For the calculation of the volume of distribution (Vd) one must take into account:

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A small amount of the volume of distribution is common for lipophylic substances easy penetrating through barriers and widely distributing in plasma, interstitial and cell fluids:

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The term “biotransformation” includes the following:

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Biotransformation of the drugs is to render them:

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Tick the drug type for which microsomal oxidation is the most prominent:

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Pick out the right statement:

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Stimulation of liver microsomal enzymes can:

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Metabolic transformation (phase 1) is:

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Biotransformation of a medicinal substance results in:

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Conjugation is:

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Which of the following processes proceeds in the second phase of biotransformation?

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Conjugation of a drug includes the following EXCEPT:

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Metabolic transformation and conjugation usually results in an increase of a substance biological activity:

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In case of liver disorders accompanied by a decline in microsomal enzyme activity the duration of action of some drugs is:

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Half life (t ½) is the time required to:

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Half life (t ½) doesn’t depend on:

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Elimination is expressed as follows:

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Elimination rate constant (Kelim) is defined by the following parameter:

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The most rapid eliminated drugs are those with high glomerular filtration rate and actively secreted but aren’t passively reabsorbed:

 

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Systemic clearance (CLs) is related with:

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Pharmacodynamics involves the study of following EXCEPT:

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Pharmacodynamics involves the study of following?

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. Pharmacodynamics involves the following?

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Pick out the answer which is the most appropriate to the term “receptor”

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. What does “affinity” mean?

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Target proteins which a drug molecule binds are:

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An agonist is a substance that:

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. If an agonist can produce maximal effects and has high efficacy it’s called:

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If an agonist can produce submaximal effects and has moderate efficacy it’s called:

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. An antagonist is a substance that: .

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The substance binding to one receptor subtype as an agonist and to another as an antagonist is called:

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A competitive antagonist is a substance that:

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Irreversible interaction of an antagonist with a receptor is due to:

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Mechanisms of transmembrane signaling are the following EXCEPT:

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Tick the second messenger of G-protein-coupled (metabotropic) receptor:

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Tick the substance which changes the activity of an effector element but doesn’t belong to second messengers:

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Pick out the correct definition of a toxic dose:

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All of the following statements about efficacy and potency are true EXCEPT:

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Give the definition for a therapeutical dose:

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Tick the substances whose mechanisms are based on interaction with ion channels

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The increase of second messengers’ (cAMP, cGMP, Ca2+ etc.) concentration leads to:

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Tachyphylaxis is:

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What term is used to describe a decrease in responsiveness to a drug which develops in a few minutes?

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What term is used to describe a more gradual decrease in responsiveness to a drug, taking days or weeks to develop?

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Which effect may lead to toxic reactions when a drug is taken continuously or repeatedly?

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Tolerance develops because of:

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Tolerance and drug resistance can be a consequence of:

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Tolerance and drug resistance can be a consequence of:

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Drug resistance is a term used to describe the loss of effectiveness of antimicrobial or antitumour drugs. This consideration is:

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Dependence is often associated with tolerance to a drug, a physical abstinence syndrome, and psychological dependence (craving). This consideration is:

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The situation when failure to continue administering the drug results in serious psychological and somatic disturbances is called?

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. What is the type of drug-to-drug interaction which is connected with processes of absorption, biotransformation, distribution and excretion?

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What is the type of drug-to-drug interaction which is the result of interaction at receptor, cell, enzyme or organ level?

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What phenomenon can occur in case of using a combination of drugs?

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If two drugs with the same effect, taken together, produce an effect that is equal in magnitude to the sum of the effects of the drugs given individually, it is called as:

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What does the term “potentiation” mean?

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The types of antagonism are:

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The term “chemical antagonism” means that:

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Teratogenic action is:

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Characteristic unwanted reaction which isn’t related to a dose or to a pharmacodynamic property of a drug is called:

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Idiosyncratic reaction of a drug is:

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Therapeutic index (TI) is:

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Increasing the proportion of the disperse phase of an emulsion by more than 60% may lead to

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The second law of thermodynamics states that 'whenever a spontaneous process takes place, it is accompanied by an increase in the total energy of the universe! The equation that satisfies the above law is :

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The complexation of Quinine with hexyl salicylate is an example of absorption by

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The polymorphs exhibit the following different properties Except :

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Method of Study Drug Distribution pattern is :

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Which of the following powder shows the greatest degree of dustibility

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The dispersion of course material by shearing in a narrow gap between a static cone and a rapidly rotating cone is caused by

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When the concentration of an aqueous sodium chloride solution has the same colligative properties as the solution in question, the value so obtained is known as

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When adhesive attractions between molecules of different species exceeds cohesive attraction between like molecules, the deviation according to Raoult's law is said to be

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Centistoke is the CGS unit for the following property

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Molar heat capacity of a system is defined as :

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