GPAT Exam 2021 Mock Test, Sample Paper 4

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By giving which you can increase your knowledge for GPAT EXAM 4, prepare yourself well, this test can prove to be very good for you, Most of the questions given in this test are taken from the old question paper of GPAT EXAM 4, so that you will also know what type of questions are asked in GPAT EXAM 4.

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Created on By Ranu Gupta

GPAT Exam 4

Based on Previous Exam

1 / 125

The mechanism of action of ciprofloxacin is:-

2 / 125

Which of the following is NOT CORRECT for myasthenia gravis?

3 / 125

Which of the following describes the effect of Sodium cromoglycate?

4 / 125

Identify antihistamine drug with additional serotonin receptor blocking activity and good appetite stimulant property.

5 / 125

Which of the following side effect of ACE inhibitors result from inhibition of bradykinin breakdown?

6 / 125

Which of the following are the mechanisms of action of digitalis glycosides?

i. Inhibition of Na+-KATPase enzyme.
ii. Reduction in the auriculo-ventricular conduction rate.
iii. Increase in the cardiac output.
iv. Acceleration of auriculo-ventric ular conduction rate.

7 / 125

 The following is NOT true for Furosemide:

8 / 125

Which of the following about the Varicella-Zoster Virus (VZV) is NOT true?

9 / 125

The rheological and functional properties of synovial fluid are impaired due to :

10 / 125

 As per US FDA, NDA’s for new chemical entitles are classified as either :

11 / 125

In preformulation study polymorphs can be detected by

12 / 125

The following is/are used to determine the amount of drug bound to a protein:

13 / 125

 In tablet, hydroxy propyl methyl cellulose is used as

14 / 125

 Movement of charged particle through a liquid under the influence of an applied potential difference is known as

15 / 125

 Dakin’s solution is a synonym for :

16 / 125

 MEDLINE, EMBASE, EBM AND IDIs are :

17 / 125

Theories of emulsification are characterized by one of the following EXCEPT:

18 / 125

When two brands of a drug product gives same clinical results, it is termed as :

19 / 125

Soda ash is also known as :

20 / 125

Microcrystalline cellulose is also called as :

21 / 125

Which of the following statement is NOT true regarding bulkiness ?

22 / 125

Amixture of emulsifier A and emulsifier B with values of 4 and 14 respectively are to be mixed in a proportion to get mixture with required HLB 12. What is the weight of individual emulsifier that is to be taken to have a total weight of 7 gm ?

23 / 125

Which of the following oxide is not used for achieving Amber color to glass ?

24 / 125

 In case of suppositories base, SFI stands for :

25 / 125

If mean volume — number diameter of a powdered sample is 2.41µm, density is 3 gm/cm3 , the number of particles/gm will be .

26 / 125

Which polymorphic form of a drug candidate has highest melting point :

27 / 125

 For bitter drugs in paediatric formulations, excellent flavouring agent will be.

28 / 125

The co-administration of erythromycin with cyclosporine :

29 / 125

Essentially Hospital Formulary system provide mechanism to :

30 / 125

 Volume of blood that flows per unit time per unit volume of the tissue is :

31 / 125

Leaching by immersion Of crude material in a solvent is also known as :

32 / 125

 The protein toxins that have been modified to reduce the toxicity without significantly altering the immunogenicity are known as :

33 / 125

Which of the following is NOT a mechanism for achieving gastroretention?

34 / 125

The phase contrast microscopy is valuable in studying living cells which are :

35 / 125

 The size Of Lycopodium sp ores is :

36 / 125

Regholarrhenines A-F have been isolated from :

37 / 125

Pungency of Zingiber officinal e rhizome is due to the presence of :

38 / 125

The principal cultivation areas of pyrethrum flowers are in -

39 / 125

 In Cassia angustifolia short-term drought :

40 / 125

 The Glycoside Scilliroside in red sqrill acts as :

41 / 125

Shellac is a resinous substance pr4vtred from a secretion that encrusts the bodies of a scale insect :

42 / 125

All members of this order are trees or shrubs; mostly evergreen with needle - like leaves ; monoecious
or dioecious - sporophylls usually in cones. Resin ducts occur in all parts :

43 / 125

In Gambir - fluorescin test the petroleum spirit layer shows a strong :

44 / 125

Antiviral action of Neem in due to :

45 / 125

Characteristic micrncapic features observed in Alzheimer’s disease is:

46 / 125

Cardiac output is:

47 / 125

 What are sutures?

48 / 125

 Following are the facts regarding clinical applications of muscarinic receptor blocking drugs. Identify the false statement:

49 / 125

Which of the following cells are called scavenger cells?

50 / 125

Which is NOT true about calcitriol?

51 / 125

Production of an abnormal lgG immunoglohulin in Grave’s disease causes:

52 / 125

 Metabolic acidosis does NOT occur during :

53 / 125

Glucocorticoids have following effects - EXCEPT:

54 / 125

 Which one of the following is NOT’ the role of Nitric oxide?

55 / 125

 Identify the drug which is not useful in the treatment of tuberculosis:

56 / 125

 What is anaplasia?

57 / 125

Match the following liver abnormalities with consequences:

58 / 125

 Numerous isomers of human liver P450 enzyme have been identified, it is not worthy that ______alone is responsible for the metabolism of over 55% of the prescription drugs metabolized by liver.

59 / 125

Which of the following directly inhibits Factor Xa?

60 / 125

 Which of the following anticonvulsants have both inhibition of excitatory glutamatergic synapse and facilitation of GABA mediated Cl channel opening action?

61 / 125

 Which of the following is NOT a cardioselective β blocker?

62 / 125

 The term ‘aneurysm’ refers to:

63 / 125

The antiemetic activity of glycopyrronium is related to potent inhibition of ........... receptor both peripherally and centrally.

64 / 125

Identify the false statement about benzodiazepines from the following:

65 / 125

Which of the following is 5-alpha reductase inhibitor?

66 / 125

Several different chemicals released by microbes and inflamed tissues attract phagocytes, this phenomenon is called as .............

67 / 125

 Hematocrit 65% to 7O% indicates:

68 / 125

 The adverse reaction associated with â-2 agonists administered by inhalation or nebulisation in the management of asthma does not include ..............

69 / 125

 Select the ulcer protective drug from the following:

70 / 125

Disturbances of oestrogen/progesterone balance could cause a relative deficiency of .......... leading to disturbances in production of dopamine and serotonin. This contributes for emotional disturbances and depression.

71 / 125

Testing of chemicals by OECD guideline No. 420 refers to which of the following:

72 / 125

 Which of the following is true?

Excessive use of diuretics can lead to:

73 / 125

 In a free radical reaction, free radicals are formed at

74 / 125

 Separating techniques such as gas chromatography and liquid chromatography are not appropriate for separation of amino acids. Select correct reason from the following

75 / 125

 When trans-2-butene is treated with bromine an anti-addition of bromine yields meso- 2,3- dibromobutane.
Select the correct statement regarding the reaction from the following

76 / 125

 Reduction of imines to give amines in protic solvents can be carried out by one of the following reagents. Select the correct reagent

77 / 125

Which of the following cannot react as a nucleophile

78 / 125

Which of the following compounds will be oxidized by CrO3 in acid

79 / 125

 Which of the following reagents will reduce a disubstituted alkyne to trans-alkene

80 / 125

. Which functional group is present in the molecule shown below

81 / 125

If the pKa of lidocaine is 7.9 and pH of the infected tissue is 8.9, the fraction of drug in the ionized form will be

82 / 125

 Which among the following are the salient features of Glucocorticoids

83 / 125

 The most commonly used test of sensitivity to antimicrobial agent is

84 / 125

 Bulk product is defined as

85 / 125

 Product,........and Promotion are four ‘P’s of marketing

86 / 125

 Insulin and thyroxin arrive at an organ / tissue / cell at the same time. Thyroxine causes an effect on the organ but insulin does not because

87 / 125

Which among the following is an incorrect statement with regard to the drug Dantrolene

88 / 125

 Diazepam is not suitable for peroral sustained release form since

89 / 125

 Antioxidant used as blocking agent in sterile product is

90 / 125

Many mediators have been implicated in the asthmatic response. The clinical efficacyof pharmacologic intervention with inhibitors or antagonist of the mediators involves following category - except

91 / 125

If the drug substance has been substituted wholly or in part by another drug orsubstance, it is called as

92 / 125

 One of the principle upon which HPLC detector functions is

93 / 125

Methanolic extract of a crude drug powder when treated with magensium turnings and concentrated hydrochloric acid turned the solution magenta coloured. The test is termed as

94 / 125

Etoposide and Teniposide are the semisynthetic derivatives of

95 / 125

For the measurement of particle size of powders, the distance measured between two tangents on opposite sides of the particle parallel to some fixed direction is called

96 / 125

Beta oxidation of fatty acids takes place in

97 / 125

Which of the following genera is not the source for tropane alkaloids

98 / 125

The useful variable from in vitro dissolution test data for IVIVC includes

99 / 125

Apparent volume of distribution will be highest in case of the drug with % plasmaprotein binding

100 / 125

 To rule out the probability of dose dumping from an oral CR dosage form, USP hasincluded which sampling time point for in vitro dissolution test where D is normal dosing interval

101 / 125

Which of the following statement regarding cerebral hemisphere is true

102 / 125

Which among the following is a Class-I method, used for rendering a solution of drug isotonic with body fluids

103 / 125

 (Weight in pounds/150) * Adult Dose = Child dose. The above formula is known as _________ in Posology

104 / 125

The type of particle diameter obtained by microscopic method of evaluation is

105 / 125

Naphazoline

106 / 125

A patient receiving warfarin develops rheumatoid arthritis. Which one of the following drugs would be Contraindicated

107 / 125

A crude drug powder was heated with ferric chloride, water and concentrated hydrochloric acid followed by extraction with chloroform. The chloroform layer was treated with ammonia, the ammonical layer turned pink. The test indicates presence of________ phytoconstitutent

108 / 125

 The first vaccine was discovered by

109 / 125

Type IV dissolution apparatus as per USP is

110 / 125

 Hoeppler viscometer is a type of

111 / 125

In relation to buccal and sublingual route of administration which of the following statement is incorrect

112 / 125

Which among the following statements describing surface activity for surfactants is incorrect

113 / 125

 Surface tension is categorized as a/an __________ factor

114 / 125

Which of the following gums is obtained from endosperm

115 / 125

High lightening differences among brands within the same product category is_________

116 / 125

Hot stage microscopy is an important tool in preformulation studies for the study of

117 / 125

 In Bismuth subgallate suppositories B.P.C, when no strength of the drug is specified, B.P.C directs __________ bismuth subgallate per suppository

118 / 125

The Michaehis-Menten hypothesis

119 / 125

 The largest gene in human is _____________

120 / 125

 Which of the following techniques is not useful to detect polymorphs

121 / 125

Which of the following constituents is responsible for colour of shellac

122 / 125

Hixon Crowell’s cube root law of dissolution states that

123 / 125

 All of the following statements regarding estrogen therapy in postmenopausal women are true EXCEPT

124 / 125

 Chapter IV of which law states that experiments on animals are avoided wherever it is possible to do so; as for example; in medical schools, hospitals, colleges and the like, if other teaching devices such as books, models, films and the. like, may equally suffice. Also, that experiments on larger animals are avoided when it is possible to achieve the same results by experiments upon small laboratory animals like guinea- pigs,rabbits, frogs and rats

125 / 125

Which among the following rules about spin - spin coupling and bond multiplicities are correct with regard to NMR spectra

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